STD Testing in Sioux Falls, SD
You can order an STD test online and give your sample at one of 19 test centers in Sioux Falls (18 Sanford Laboratories and 1 Quest Diagnostics) used by STDcheck and HealthLabs. Single tests start at $39 with STDcheck's coupon, and the Full STD Panel is $139 ($129 with code 10OffOrder). There's no doctor's visit or insurance involved, and STDcheck says results come back in 1–2 days. 4 of the Sioux Falls centers open on Saturday, and 3 more are within 15 miles.
Order an STD test for Sioux Falls
The price is the same at every Sioux Falls test center. Order online, choose your center from the provider's list, give your sample, and see results online.
We may earn a commission when you order through our links. Your price is the same. Details
| Test | Provider | Price | Order |
|---|---|---|---|
| Chlamydia & Gonorrhea Combined Test | STDcheck | $99 $89 with code | Order |
| Chlamydia Test | STDcheck | $59 $49 with code | Order |
| HIV 1 & 2 Antibody Test | STDcheck | $49 $39 with code | Order |
| Syphilis Test | STDcheck | $49 $39 with code | Order |
| Herpes 1 & 2 Test | STDcheck | $79 $69 with code | Order |
| Full STD Panel Panel | STDcheck | $139 $129 with code | Order |
| Extended STD Panel Panel | STDcheck | $259 | Order |
See all 32 STD tests and panels →
Test centers in Sioux Falls
The 19 centers STDcheck and HealthLabs list in Sioux Falls, across ZIP codes 57103, 57104, 57105, 57106, 57107, 57108, 57110. Hours are as listed by the providers on October 27, 2026; check before you go.
Source: STDcheck and HealthLabs test-center finder, checked October 27, 2026. SafeHealthCheck isn't affiliated with these labs; you don't book or pay at the center.
More test centers within 15 miles
- Sanford Laboratories, 111 N Cliff Ave, Harrisburg, SD 57032 · 6.5 mi from central Sioux Falls · Directions
- Sanford Laboratories, 1105 E Holly Blvd, Brandon, SD 57005 · 9.7 mi from central Sioux Falls · Directions
- Sanford Laboratories, 905 N Oaks Ave, Hartford, SD 57033 · 12.8 mi from central Sioux Falls · Directions
You choose your exact center after ordering.
Free and low-cost testing in Sioux Falls
If cost is the main concern, public-health clinics in South Dakota may offer free or lower-cost testing, usually with set hours or appointments. Ordering online is the faster option when you want to choose the time and place yourself.
- CDC GetTested locator: Search by ZIP code for free and low-cost STD and HIV testing sites near you.
Questions about STD testing in Sioux Falls
How much does STD testing cost in Sioux Falls?
Ordered online, single STD tests start at $39 with STDcheck's $10 coupon, and the Full STD Panel costs $139 ($129 with the code). The price is the same at all 19 Sioux Falls test centers. Public-health clinics in South Dakota may offer free or lower-cost testing.
Is there a Sanford Laboratories test center in Sioux Falls?
Yes, 18: 4405 E 26th St (ZIP 57103); 1309 W 17th St (ZIP 57104); 1205 S Grange Ave, Suite G01 (ZIP 57105); 1321 W 22nd St. (ZIP 57105); 2701 S Kiwanis Ave (ZIP 57105); 1420 W 22nd Street, Suite G01 (ZIP 57105); 3401 W 49th St (ZIP 57106); 2601 S Ellis Road (ZIP 57106); 4000 N Hercules Ave (ZIP 57107); 4000 N Brendan Lane (ZIP 57107); 6101 S Louise (ZIP 57108); 6110 South Minnesota Ave (ZIP 57108); 5019 S Western Ave (ZIP 57108); 5019 S Western Ave, Suite 200 (ZIP 57108); 6101 S Louise Ave (ZIP 57108); 6110 S Minnesota Ave (ZIP 57108); 600 N Sycamore Ave (ZIP 57110); 5920 E Madison St (ZIP 57110).
Is there a Quest Diagnostics test center in Sioux Falls?
Yes, one: 7600 S Minnesota Ave, Ste 101 (ZIP 57108).
Which Sioux Falls test center opens earliest?
The Sanford Laboratories at 1205 S Grange Ave, Suite G01 opens at 6:30 AM (Mon-Fri 6:30 AM-5:30 PM, Sat 8:00 AM-12:00 PM). The latest closing time listed is 9:00 PM, at the Sanford Laboratories on 4405 E 26th St.
Are any Sioux Falls test centers open on Saturday?
Yes: Sanford Laboratories, 4405 E 26th St; Sanford Laboratories, 1205 S Grange Ave, Suite G01; Sanford Laboratories, 1420 W 22nd Street, Suite G01; Sanford Laboratories, 4000 N Brendan Lane. Hours can change, so check before you go.
STD testing near Sioux Falls
All STD testing locations in South Dakota → · All states →
SafeHealthCheck is a comparison site, not a clinic or lab. Prices come from each provider's website and can change; the provider's checkout shows the final price. SafeHealthCheck does not provide medical advice.